Getting the Right Care to the Right Patient at the Right Time

Sepsis Poses Clinical and Operational Challenges for Providers

1/5 patients

Who present to the ED are potentially septic, requiring significant evaluation and slowing throughput1

Up to 21%

Of patients who experience sepsis have a delayed or misdiagnosis2

78.1 – 93.0

Range in NPV for sepsis from blood cultures, lactate, and procalcitonin3

62%

Of ED physicians report experiencing burnout4

  1. Wang HE, Jones AR, Donnelly JP. Revised national estimates of emergency department visits for sepsis in the United States. Crit Care Med. 2017;45:1443-1449.
  2. Neilson HK, Dobranowski J, Baxter S, et al. Diagnostic delays in sepsis: Lessons learned from a retrospective study of Canadian medico-legal claims. Crit Care Explor. 2023;5(2).
  3. O’Neal, et al. Assessment of a Cellular Host Response Test as a Sepsis Diagnostic for Those With Suspected Infection in the Emergency Department. Crit Care Explor. 2021;3(6). 
  4. American Medical Association. These 6 physician specialties have the most burnout. AMA. 2023. https://ama-assn.org/practice-management/physician-health/these-6-physician-specialties-have-most-burnout.

All results should be interpreted in the context of the other clinical observations and laboratory test results for the patient

IntelliSep Now Offers Early Sepsis Detection with Clear, Actionable Results

IntelliSep is a diagnostic tool that risk-stratifies patients based on their probability of developing sepsis within 3 days post-testing. IntelliSep delivers results in about 8 minutes, enabling care teams to provide faster, more personalized care.

IntelliSep is an FDA-cleared in vitro diagnostic test for adult patients with signs and symptoms of infection who present to the Emergency Department

Application of Early Sepsis Detection Begins in Triage

Incorporating the IntelliSep sepsis test into your ED workflow at the time of triage provides a more reliable, objective measure for identifying patients’ risk of sepsis, leading to more accurate and timely diagnosis and treatment. 

  1. O’Neal et al. Pooled analysis. Presented at: Academic Emergency Medicine Annual Meeting (AEM); 2024.

Expected Impact of IntelliSep

Expedite diagnoses1 and disposition decisions, leading to more efficient resource allocation, shorter ED wait times, decreased boarding, and optimized bed usage2 

Provide the right treatment to the right patients, leading to improved antimicrobial stewardship and shorter length of stay, while complying with SEP-1 guidelines3

Empower clinicians to identify and prioritize critically ill patients with confidence, contributing to less burnout, stronger teamwork, and improved retention

  1. T Jagneaux, et. al. Expediting Identification of Occult Sepsis with a Novel Diagnostic for Patients Presenting to the ED with Possible Infection. Presented at Association for Diagnostics and Laboratory Medicine (ADLM); 2024.
  2. Our Lady of the Lake Regional Medical Center. From Test to Treatment: Clinical Interpretation, Rationale, and Impact of the IntelliSep Test. Case study. 2024.
  3. Thomas CT et al. Fiscal impact of a rapid sepsis diagnostic in the ED. Presented at ISICEM; March 19, 2024; Brussels, Belgium. Presented by Hollis O’Neal Jr., MD, MSc.

Providing Better Care for ED Patients: One Hospital’s Experience with IntelliSep

Our Lady of the Lake Regional Medical Center’s Emergency Department uses IntelliSep to enhance its sepsis triage protocols, resulting in significant improvements in care for patients who are potentially septic.

IntelliSep Early Impact at a 900+ Bed Regional Medical Center

Reduction in LOS of patients with ISI ordered1

Reduction in antibiotics administered to patients with ISI ordered2

Reduction in blood cultures ordered for patients with ISI ordered2

Reduction in overhead sepsis alerts per day3

“The IntelliSep test helped to identify my sepsis early, leading to immediate and necessary treatment. I believe the test was crucial in saving my life. I can’t speak highly enough of the test—and I can’t  imagine a hospital not having it.”

Learn more about Terri’s experience