- Brenda Fitzgerald, M.D. (CDC Director)
Sepsis is the #1 cause of death in hospitals, taking the lives of 270,000 people every year in the United States, which is more than opioid overdoses, prostate cancer and breast cancer combined.
Mortality from sepsis increases as much as 8% for every hour that treatment is delayed. As many as 80% of sepsis deaths could be prevented with rapid diagnosis and treatment – making early detection essential.
Sepsis related healthcare costs in the U.S. are astronomical – something we can help dramatically reduce with consistent early detection.
With sepsis, the patient’s immune system, or host response, becomes dysregulated, leading to collateral damage of blood vessels and major organs, such as the kidneys and liver. We directly see this dysregulation as structural shifts in white blood cells.
Controlled, effective immune response
at the site of the infection
Uncontrolled amplification of immune
response throughout the entire body
Sepsis doesn’t discriminate based on age, gender or health status and it presents non-specifically, with up to 85%2 of cases coming through the emergency department. With current approaches, sepsis remains challenging to diagnose early and accurately, often consuming valuable resources and delaying care to those who need it most.
Sepsis places a devastating burden on patients and their families. It also has broad impact across hospitals, including:
We’ve enrolled thousands of patients in our clinical studies to advance early sepsis detection in the emergency department in an effort to find ways to significantly reduce morbidity and mortality, and decrease healthcare costs.
1 Radius Global Market Research. (2019). Sepsis Awareness Study Summary Report. Sepsis Alliance.
2 Mark Ramzy, DO, "Early Sepsis Screening in the Emergency Department", REBEL EM blog, December 10, 2018.