Saving Lives with Rapid,

Real-World Impact
After six months of using IntelliSep, our results show that a higher percentage of patients are returning home to their families earlier, at lower cost for them and the hospital. Our ability to improve patient flow has been revolutionary.”
Dr. Christopher Thomas
Chief Quality Officer Franciscan Missionaries of Our Lady Health System

IntelliSep: One Site’s Experience

Relative risk reduction in 30-day
sepsis associated mortality rate

Reduction in blood cultures among low-risk Band 1 patients

Increase in blood cultures among high-risk
Band 3 patients

Reduction in average LOS for sepsis patients

Estimated cost savings per sepsis patient due to reduction in LOS

Reduction in Code Sepsis
alerts from 30 to 6 per day

Increased speed-to-bed for Band 3
patients compared to Band 1 patients,
enabled by IntelliSep and Code Sepsis protocol

Absolute increase in SEP-1 compliance
while reducing use of resources
The above Impact Notes regarding IntelliSep were generated by the Emergency Department of an 900-Bed Regional Medical Center over a 90-day period and were based on their institutional practices and site validation of IntelliSep.
See the IntelliSep Test Instructions for Use for all cleared claims and performance data.
- Thomas CB, Wyler B, D’Antonio CM, Laperouse M, et al. Impact of a Sepsis Quality Improvement Initiative on Clinical and Operational Outcomes.Healthcare. 2025; 13(11):1273.
- AHRQ Report to Congress: An Assessment of Sepsis in the United States and its Burden on Hospital Care (2023)
- Assuming average $2,941 cost per inpatient day; $25,000 per sepsis admission and LOS of 8.5 days
- Jagneuax T, et al. Expediting Identification of Occult Sepsis with a Novel Diagnostic for Patients Presenting to the ED with Possible Infection (2024).
- Data on file.

From Test to Treatment: Clinical Interpretation, Rationale, and Impact of the IntelliSep Sepsis Test
Real-World Results
Our Lady of the Lake
Regional Medical Center
IntelliSep has been seamlessly integrated into clinical workflows at Our Lady of the Lake Regional Medical Center. It has improved triage for patients with suspected sepsis, reducing time to diagnosis, and allowing for more efficient use of antibiotics and blood cultures, thereby optimizing resource utilization. These streamlined processes and care pathways have resulted in substantial clinical benefit as well as cost savings. This document presents a detailed exploration of Our Lady of the Lake Regional Medical Center’s strategy to address sepsis in the ED, improve triage, and develop an effective clinical interpretation and application of the test.