Past Publications

Assessment of a cellular host response test to risk-stratify suspected COVID-19 patients in the Emergency Department setting
March 17, 2022

Assess the IntelliSep Index (ISI) for risk stratification of patients presenting to the Emergency Department (ED) with respiratory symptoms suspected of COVID-19 during the pandemic. An observational ...

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Assessment of a Cellular Host Response Test as a Sepsis Diagnostic for Those With Suspected Infection in the Emergency Department
June 22, 2021

Sepsis is a common cause of morbidity and mortality. A reliable, rapid, and early indicator can help improve efficiency of care and outcomes. To assess the IntelliSep test, a novel in vitro diagnostic...

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Development and validation of a cellular host response test as an early diagnostic for sepsis
April 21, 2021

Sepsis must be diagnosed quickly to avoid morbidity and mortality. However, the clinical manifestations of sepsis are highly variable and emergency department (ED) clinicians often must make rapid, im...

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Rapid Biophysical Analysis of Host Immune Cell Variations Associated with Sepsis
July 18, 2018

This correspondence provides an overview of how our automated deformability cytometry instrument and microfluidic cartridge is used to measured shifts in the biomechanical properties of immune cells, s...

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Quantitative Diagnosis of Malignant Pleural Effusions by Single-Cell Mechanophenotyping
November 20, 2013

In this paper, we conducted the first large scale clinical study evaluating the use of cellular mechanical biomarkers from thousands of single-cells as a diagnostic. The report provides evidence that ...

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A Mechanical Biomarker of Cell State in Medicine copy
January 27, 2012

This review highlights the opportunities to improve clinical diagnostics using mechanical measurements of populations of single-cells as unique biomarkers. These biomarkers are argued to that have som...

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